ISLAMABAD: — Researchers have uncovered a major breakthrough in the treatment and prevention of Type 2 diabetes, offering new hope to millions of patients worldwide.
A study published in Nature Communications highlights the role of a gene called SMOC1, which appears to play a central role in the onset of the disease. The discovery opens the door to the development of more effective therapies targeting the underlying causes of Type 2 diabetes.
According to the research, SMOC1 affects specialized cells in the pancreas responsible for regulating blood sugar levels. When this gene becomes overactive, the insulin-producing beta cells lose their identity and start producing glucagon instead of insulin, leading to elevated blood sugar levels and worsening diabetes symptoms.
In healthy individuals, a balance between beta and alpha cells maintains stable blood sugar. However, in Type 2 diabetes patients, this balance is disrupted, causing insufficient insulin production and excessive glucagon release.
Experts believe that understanding this genetic mechanism is a significant step toward precision medicine for diabetes, enabling treatments that target the root cause rather than just managing symptoms. Future therapies may restore beta cell function, improving patients’ quality of life and potentially slowing or reversing the disease’s progression.
The discovery is being hailed as a potential milestone in diabetes research, with implications not only for treatment but also for early detection and prevention strategies for at-risk individuals.
